Jazz Reports Results of JZP-258 in a P-III Study to Treat Cataplexy and Excessive Daytime Sleepiness in Patients with Narcolepsy
Shots:
- The P-III study involves assessing of JZP-258 vs PBO in 201 patients in ratio (1:1) with narcolepsy prior treated with sodium oxybate and naïve to sodium oxybate with/out anti-cataplectic treatments
- The P-III study resulted in meeting its 1EPs & 2EPs i.e, reduction in the weekly number of cataplexy attacks and Epworth Sleepiness Scale (ESS) score respectively
- JZP-258 is a novel oxybate product candidate with a unique composition of cations resulting in 92% less sodium than Xyrem (sodium oxybate), currently being evaluated to treat cataplexy and excessive daytime sleepiness in narcolepsy and idiopathic hypersomnia
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