Genentech and AC Immune’s Semorinemab Flounders in P-II TAURIEL Study for Early Alzheimer’s Disease

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The P-II TAURIEL study involves assessing of semorinemab vs PBO in 457 patients with early AD across 97 sites
Genentech divulges that the P-II TAURIEL study did not meet its co-1EPs of efficacy (reducing decline on CDR-SB) but meets its 1EPs of safety while the two 2EPs (ADAS-Cog13 & ADCS-ADL) was not met, results will be presented at the upcoming medical congress
The second P-II LAURIET study of semorinemab in patients with moderate AD remains ongoing. Additionally, IND enabling studies are ongoing for first-in-class therapeutic candidates targeting TDP-43 and alpha-synuclein

Click here to read full press release/ article | Ref: PRNewswire | Image: Fortune