Regeneron’s REGEN-COV Antibody Cocktail Confirms its Effectiveness Against UK and South Africa SARS-CoV-2 Variants

Shots:

• REGEN-COV neutralizes the SARS-CoV-2 B.1.1.7 variants, identified in the UK & SA. The data was included in a bioRxiv paper and submitted for peer-reviewed publication on the changing resistance of SARS-CoV-2 variants to Ab neutralization
• REGEN-COV retained its neutralizing capability against the B.1.1.7 variant. The Ab cocktails also retained its potency against the B.1.351 variant; imdevimab retained its potency against it while casirivimab potency was reduced
• Additionally, the Brazil variant (1.1.248) have the same receptor binding domain mutations as the B.1.351, thus REGEN-COV is expected to remain similarly potent. Regeneron is conducting additional research against this strain

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