Merck KGaA and GSK Terminate their ~$4.2B Collaboration Due to Clinical Failures

 Merck KGaA and GSK Terminate their ~$4.2B Collaboration Due to Clinical Failures

Merck KGaA Collaborated with Burning Rock for Liquid-biopsy Based CDx Development

Shots:

  • The companies terminated their collaboration that centered around bintrafusp alfa as the drug failed to show potential in INTR@PID Lung 037 study as the 2L treatment for metastatic BTC
  • The termination followed a decision made by the two companies to discontinue the development of bintrafusp alfa as a 1L therapy for patients with stage IV NSCLC and high expression of PD-L1
  • IDSM board recommended the termination of the P-III study in which bintrafusp + Keytruda was not likely to meet its 1EPs of PFS

Click here to­ read full press release/ article | Ref: Merck KGaA | Image: CHEManager