Ultimovacs Reports Results of 24-month Follow-up Study of UV1 + Pembrolizumab for 1L Treatment of Metastatic Malignant Melanoma

 Ultimovacs Reports Results of 24-month Follow-up Study of UV1 + Pembrolizumab for 1L Treatment of Metastatic Malignant Melanoma

Ultimovacs Reports Results of 24-month Follow-up Study of UV1 + Pembrolizumab for 1L Treatment of Metastatic Malignant Melanoma

Shots:

  • In a P-I study, patients were treated initially for 14wks. with UV1 + pembrolizumab and patient in the first cohort had been followed for at least 24mos. from the start of their treatment, @ cut-off date of Oct 12, 2021
  • After @2yrs. follow up, OS (80%) in the first cohort of 20 patients. mPFS (18.9mos.). The 24mos. follow-up data compares favorably with an earlier large-scale study of pembrolizumab alone that demonstrated an OS rate of 58% after 24mos. and mPFS of 5.5-11.6mos.
  • The 2yrs. follow-up data suggested that the way in which UV1 mobilizes the immune system provides long benefits to the patients

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