Daiichi Sankyo and AstraZeneca Entered into a Second Clinical Trial Collaboration with Merck for Datopotamab Deruxtecan (Dato-DXd) + Keytruda (pembrolizumab)

Shots:

• The companies collaborated to evaluate datopotamab deruxtecan + Keytruda vs Keytruda alone in P-III TROPION-Lung08 trial in ~740 patients with PD-L1 high advanced or metastatic NSCLC without actionable genomic alterations over multiple sites in Asia, EU, North & South America
• The 1EPs of a trial are PFS & OS. Additionally, the second clinical trial collaboration is based on the results in an ongoing P-Ib study
• In Jul’20, Daiichi Sankyo has entered into a collaboration with AstraZeneca to develop and commercialize datopotamab deruxtecan except in Japan. Daiichi Sankyo maintains exclusive rights  & is responsible for the manufacturing & supply of datopotamab deruxtecan

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